After much testing.....
The ETU: Settings and the ETU: Theme make no difference when loaded at startup.
I don't see that they interfere with any other theme that is loaded at the same time.
So far there is no reason to load either.
All the game information is located in the modules you load at the start.
I select Savage Worlds Deluxe as my ruleset and upon loading it loads both SWD and SWADE, so I'm not messing with it.
Although not a fan of the Wild West setting, the Deadlands reloaded theme is useable.
As always thanks for the help
mindfungus